What will be used to measure the sound intensity of ultrasonic waves in liquids?
When the pressure of the sound wave propagated by ultrasonic vibration in the liquid reaches one atmospheric pressure, its power density is 0.35w/cm2. At this time, the peak value of the sound wave pressure of the ultrasonic wave can reach vacuum or negative pressure, but there is actually no negative pressure, so in the liquid A great pressure is generated to pull the liquid molecules into cavitation nuclei.
This is a series of dynamic processes such as contraction, expansion, oscillation and implosion of microbubbles in the liquid under the action of ultrasound, accompanied by various energy release behaviors such as transient high pressure, high temperature, discharge, shock wave and microjet. This effect acts on the tissue interface, breaking the cell wall and plasma membrane, increasing the permeability of the cell membrane, and producing reversible or irreversible pores, which is the acoustic pore effect produced by ultrasonic cavitation.
When the sound intensity is low:
The sound pressure directly affects the radial vibration of the bubbles. The microbubbles oscillate several times in the direction of the equilibrium radius. A microbeam will be generated around each microbubble, which can generate a high stress on the bubble surface, causing the bubble to deform and break, and it will Affect surrounding cells and biological macromolecules, and produce corresponding biological effects.
When the sound intensity is high:
The oscillation of the bubble becomes controlled by the inertia of the surrounding medium. The cavitation nucleus expands rapidly during the half cycle of the negative pressure phase of the ultrasonic field. During the half cycle of the positive pressure phase, the cavitation nucleus rapidly contracts until it implodes, which is called inertial cavitation or instantaneous cavitation. Instantaneous cavitation can produce local high pressure and high temperature in the final stage, accompanied by the generation of free radicals and powerful shock waves. These forces can kill tumor cells, but also have great lethality on normal cells. Adding ultrasonic microbubbles can increase the cavitation nucleus and enhance the cavitation effect. In addition, the cavitation effect is affected by many other factors, such as the frequency and intensity of ultrasound, and the nature of the liquid.
The targeting effect of ultrasound microbubbles is divided into active targeting and passive targeting. Active targeting means that the surface of the microbubbles has been treated in different ways, such as surface modification of specific antigens, specific receptors, and ligands, or the binding of microbubbles to the target through avidin-biotin, so that it can be targeted Visualization, to achieve the purpose of targeted diagnosis and targeted therapy. Passive targeting means that the microbubbles are not surface-modified, and use their own charge and chemical properties to stay in the diseased tissue to achieve a certain degree of targeting.
The samples are processed by the principles of ultrasonic ablation and magnetic field transformation, and some related instruments or equipment are designed, which can quickly, efficiently and stably perform DNA, RNA, protein extraction and other analysis and testing experiments of animal tissues.
Our ultrasonic sound intensity measuring instrument is a device specially used for measuring the ultrasonic sound intensity in liquid. The so-called sound intensity is the sound power per unit area, and the size of the sound intensity directly affects the effects of ultrasonic cleaning, ultrasonic emulsification, ultrasonic extraction, and ultrasonic dispersion.
Advantages of ultrasonic sound intensity measuring instrument
1. The measuring instrument is exquisite in design, reasonable in structure, simple in operation and accurate in measurement.
2. The equipment is simple to install, easy to operate, widely applicable, and ready to use.
Contact Person: Ms. Hogo Lv