What Are The Applications Of Ultrasonic In The Extraction Of Active Ingredients Of Traditional Chinese Medicine?
The chemical composition of traditional Chinese medicine is very complex, and the extraction of its active ingredients is an important part of the field of traditional Chinese medicine research. The active ingredients of traditional Chinese medicine generally refer to chemical substances with clear chemical structural formulas and physical constants. If the concentration of active ingredients is not high, the dosage will be increased. At the same time, the existence of ineffective or low efficacy parts will make traditional Chinese medicines easy to absorb moisture. Deterioration and difficult to preserve, so it is necessary to extract and separate the active ingredients of traditional Chinese medicine. Many effective chemical components in traditional Chinese medicine are intracellular components, and cells or cell membranes need to be broken during extraction. However, the existing chemical and mechanical methods for breaking cells are often difficult to achieve the desired breaking effect, thus affecting the extraction results.
Ultrasonic extraction has shown obvious advantages in the extraction of chemical components of traditional Chinese medicine because of its unique extraction mechanism and ideal extraction effect. Ultrasonic-assisted extraction technology uses the strong vibration, high acceleration, strong cavitation effect and strong stirring effect of ultrasonic waves to shorten the time for the active ingredients of natural products to enter the solvent, speed up the extraction process, improve the extraction rate, and effectively avoid high temperature damage to the active ingredients.
In recent years, with the vigorous development of natural product modernization research and ultrasonic technology, many researchers have introduced the technology into an important part of natural product production—the extraction process of active ingredients.
In the product component extraction process, the process of breaking the cell wall and extracting the cell contents efficiently and quickly is realized. Since the first generation of ultrasonic waves in 1830, it has been widely used in many fields such as food, medical care and household appliances, and is manifested in ultrasonic extraction, ultrasonic drying, ultrasonic sterilization, ultrasonic filtration, and ultrasonic cleaning. Among them, the ultrasonic extraction method is a method that uses the cavitation, mechanical action and thermal effect of ultrasonic waves to increase the frequency and speed of the molecular motion of the substance, increase the penetration force of the solvent, and thereby improve the leaching rate of the target component.
It has the advantages of time saving, energy saving and high extraction efficiency. It is a fast and efficient new extraction method, and there is no heating process in the extraction, which can avoid changes in the structure of drug components caused by heating factors, and can be used for the extraction of heat-sensitive components. Ultrasonic extraction has been widely used in sample processing for quality testing of traditional Chinese medicines.
In recent years, its application in the extraction process of traditional Chinese medicine preparations has also attracted more and more attention, and important progress has been made. Ultrasound used in plant sample extraction is generally generated by magnetic materials through a converter, and the effective frequency is generally in the range of 20-50kHz. It is now believed that its cavitation, thermal effect and mechanical effect are the effects of ultrasonic technology in traditional Chinese medicine extraction. Three theoretical bases.
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