Ultrasound drug release stent spraying
Abstract: In recent years, due to the continuous improvement of people's living standards, the incidence of cardiovascular diseases known as "rich and disease-free" has been on the rise. As a result, there is a growing market demand for intervention products for micro-trauma. Drug-releasing stent has emerged, the current drug-releasing stent has achieved good results of previous clinical application, but there are still some inherent defects.
Key words: drug release stent spraying
At present, the annual demand for drug delivery stents in China is above 200,000 and the market capacity is over 1.6 billion yuan. With the help of disposable auxiliary therapeutic equipment, the total sales volume is about 2.5 billion yuan and the market potential is extremely high huge. However, most of the domestic market for drug delivery stent is monopolized by imported products. However, a small amount of domestic drug delivery stent sold on the market mainly imitates foreign products, while foreign products are used in the production process and manufacturing equipment. The core technologies are still in foreign countries. Therefore, research and development of a good therapeutic drug release scaffold need to develop their own production equipment and manufacturing processes, production equipment and manufacturing processes surface coating process plays an important role in the effectiveness of drug release scaffold, so the development of excellent coating Production process is an urgent task, with very important practical significance.
Our company applies the principle of ultrasonic atomizing spraying to the coating preparation process of the drug releasing stent, studies and develops a set of ultrasonic spraying equipment, and based on this, improves the integration of a new drug releasing stent spraying equipment - ultrasonic medical spraying equipment . Ultrasonic medical spray equipment is the use of ultrasonic transducer ultrasonic waves generated through the atomization medium, the formation of surface tension wave at the gas-liquid interface, due to ultrasonic cavitation liquid molecules force destruction, prolapse from the liquid surface to form droplets, The liquid is atomized. Ultrasound medical spraying equipment improved atomization particles up to about 10 microns, the drug release stent surface can form a uniform and dense coating.
Traditional coating preparation methods, such as meteorological deposition, magnetron sputtering, plasma deposition and the like generally require expensive equipment and are not conducive to mass production of the stent. The method explored by our company is simple and convenient, Release coating stent industrialization process.
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